We research the genetic, physiological, cellular and structural basis of the brain, the cardiovascular system, the intestine, the pancreas and the liver in order to detect neurodegenerative diseases - such as Parkinson's and Alzheimer's - or metabolic diseases - such as diabetes mellitus - at an early stage and to gain knowledge for their treatment or early detection. To this end, we use, among others, the model systems: Drosophila and C. elegans.